Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Epithelial Cell, Cell Culture
DISEASE(S): Breast Cancer
SUBMITTER: li tang
LAB HEAD: Feng Yan
PROVIDER: PXD037317 | Pride | 2023-10-24
REPOSITORIES: Pride
Tang Li L Wei Da D Xu Xinyu X Mo Dongping D Cheng Daofu D Yan Feng F
Breast cancer research and treatment 20230828 2
<h4>Purpose</h4>Overactivated neddylation is considered to be a common event in cancer. Long non-coding RNAs (lncRNAs) can regulate cancer development by mediating post-translational modifications. However, the role of lncRNA in neddylation modification remains unclear.<h4>Methods</h4>LncRNA cytochrome P450 family 1 subfamily B member 1 antisense RNA 1 (CYP1B1-AS1) expression in breast cancer tissues was evaluated by RT-PCR and TCGA BRCA data. Gain and loss of function experiments were performed ...[more]