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Proteomics of antler protein extract and rat skin tissue

ABSTRACT: In this experiment, a rat model of full-thickness skin resection was used to observe the effect of antler protein extract ( PAE ) on wound healing, and its pharmacodynamic effect on wound healing and possible regulatory mechanism were further analyzed. Rats were randomly divided into PAE group and No treat group ( NT ) after 1 day of modeling. NT external physiological saline 100μl ; pAE dissolved antler protein extract ( 8mg / ml ) with normal saline, and skin tissue was taken for proteomic identification at 5D and 10D.

INSTRUMENT(S):

ORGANISM(S): Theileria Sp. Ex Hiroshima Sika Deer

TISSUE(S): Skin

DISEASE(S): Wounds And Injuries

SUBMITTER: lishuang Li

LAB HEAD: Lishuang Li

PROVIDER: PXD037328 | Pride | 2026-02-09

REPOSITORIES: Pride

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			Action	DRS
	TEclipse_FAIMS_TMT_F1.raw	Raw
	TEclipse_FAIMS_TMT_F10.raw	Raw
	TEclipse_FAIMS_TMT_F2.raw	Raw
	TEclipse_FAIMS_TMT_F3.raw	Raw
	TEclipse_FAIMS_TMT_F4.raw	Raw

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Publications

Pilose antler extract promotes angiogenesis and vascular maturation to accelerate wound healing.

Li Lishuang L Wang Yi Y Ma Yuman Y Gong Junxiao J Ren Xing X Sun Yanan Y

Scientific reports 20251229 1

Angiogenesis plays a crucial role in early wound healing by providing essential nutrients and oxygen to tissue cells, supporting the growth of epithelial cells and other tissue cells. The essence of angiogenesis lies in the proliferation and migration of endothelial cells. Pilose antler extract (PAE) accelerates early-stage wound healing. Proteomic analysis shows its role in vascular tension regulation, cell migration, and angiogenesis. This study aims to investigate the effects and pharmacologi ...[more]

PMID: 41466073

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