Ontology highlight
ABSTRACT:
INSTRUMENT(S): TripleTOF 5600
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Cell Culture
SUBMITTER: Marcello Manfredi
LAB HEAD: Marcello Manfredi
PROVIDER: PXD037551 | Pride | 2024-01-26
REPOSITORIES: Pride
Monti Matilde M Benerini Gatta Luisa L Bugatti Mattia M Pezzali Irene I Picinoli Sara S Manfredi Marcello M Lavazza Antonio A Vanella Virginia Vita VV De Giorgis Veronica V Zanatta Lucia L Missale Francesco F Lonardi Silvia S Zanetti Benedetta B Bozzoni Giovanni G Cadei Moris M Abate Andrea A Vergani Barbara B Balzarini Piera P Battocchio Simonetta S Facco Carla C Turri-Zanoni Mario M Castelnuovo Paolo P Nicolai Piero P Fonsatti Ester E Leone Biagio Eugenio BE Marengo Emilio E Sigala Sandra S Ronca Roberto R Perego Michela M Lombardi Davide D Vermi William W
Journal of translational medicine 20240108 1
<h4>Background</h4>Mucosal Melanomas (MM) are highly aggressive neoplasms arising from mucosal melanocytes. Current treatments offer a limited survival benefit for patients with advanced MM; moreover, the lack of pre-clinical cellular systems has significantly limited the understanding of their immunobiology.<h4>Methods</h4>Five novel cell lines were obtained from patient-derived biopsies of MM arising in the sino-nasal mucosa and designated as SN-MM1-5. The morphology, ultrastructure and melano ...[more]