Proteomics

Dataset Information

0

Immunopeptidomics analysis of mesothelmia cell line


ABSTRACT: We have analysed a patinet derived mesothelioma cell line by immuniopeptidomics and identified cancer antignes in this line immunopeptidome.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung, Permanent Cell Line Cell

DISEASE(S): Disease Free

SUBMITTER: Pouya Faridi  

LAB HEAD: Anthony Purcell

PROVIDER: PXD037845 | Pride | 2025-05-06

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
F120181122_PF_meso_Human_pool1.mgf Mgf
F120181122_PF_meso_Human_pool1.raw Raw
F120181122_PF_meso_Human_pool10.mgf Mgf
F120181122_PF_meso_Human_pool10.raw Raw
F120181122_PF_meso_Human_pool2.mgf Mgf
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Publications

Multiple Classes of Antigen Contribute to the Antigenic Landscape of Mesothelioma.

Pandey Kirti K   Faridi Pouya P   Ayala Rochelle R   Lee Y C Gary YCG   Rouse Ebony E   Krishna Sanjay S G SSG   Dick Ian I   Redwood Alec A   Robinson Bruce B   Creaney Jenette J   Purcell Anthony W AW  

Molecular & cellular proteomics : MCP 20250205 3


Mesothelioma is an incurable, asbestos-exposure-related cancer that typically affects the lining or pleura of the lungs. Symptoms typically develop many decades after initial asbestos exposure, leaving an enduring legacy of disease. The current disease burden is peaking worldwide and thus there is a massive unmet clinical need for curative therapies. Recently, immune checkpoint blockade-based therapy has been adopted as a first-line of treatment for mesothelioma. Vaccine-induced augmentation of  ...[more]

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