Proteomics

Dataset Information

Novel compounds modulating Mycobacterium marinum ESX-5 secretion display anti-mycobacterial activity in vivo

ABSTRACT: We observed through Western blot that Mycobacterium marinum secreted more highly abundant PE-PGRS proteins that are above 130 kDa when treated with compound 36 than mock-treated bacteria. We would like to explore which PE-PGRS proteins are more secreted in this condition and whether other proteins are also differentially secreted between two conditions.

INSTRUMENT(S):

ORGANISM(S): Mycobacterium Marinum Atcc Baa-535 Bacteria

DISEASE(S): Tuberculosis

SUBMITTER: Sander Piersma  

LAB HEAD: Connie Jimenez

PROVIDER: PXD037981 | Pride | 2023-01-19

REPOSITORIES: Pride

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Dataset's files

Source:
Action DRS
PXD037981_community_annotated.sdrf.tsv Tabular
Qe211220_OPL2014_RU_VH_medmic_compound36_A.raw Raw
Qe211220_OPL2014_RU_VH_medmic_compound36_A_211221083522.raw Raw
Qe211220_OPL2014_RU_VH_medmic_compound36_B.raw Raw
Qe211220_OPL2014_RU_VH_medmic_compound36_B_211221103805.raw Raw
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