Quantitative proteome analysis to map the targets of small molecule UM171

ABSTRACT: Earlier we identified the protein degradation properties of small molecule UM171 (Subramaniam et al., 2020, Blood). Here we employed quantitative proteomics approach to map the global targets of UM171. Our study revealed multiple targets including the members of CoREST complex such as RCOR1 and LSD1.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Sudip Ghosh  

LAB HEAD: Jenny Hansson

PROVIDER: PXD037999 | Pride | 2023-03-30

REPOSITORIES: Pride