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Protein identification of BS3 crosslinked Shigella flexneri type III secretion system needle complex

ABSTRACT: Protein identification of BS3 crosslinked Shigella flexneri type III secretion system needle complex

INSTRUMENT(S):

ORGANISM(S): Shigella Flexneri 5a

SUBMITTER: Zhuo Chen

LAB HEAD: Juri Rappsilber

PROVIDER: PXD038227 | Pride | 2026-05-05

REPOSITORIES: Pride

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Dataset's files

Source:

			Action	DRS
	B200208_10_Lumos_ZC_QC_120_xT3SS-ID.raw	Raw
	GenBank_CP037923.fasta	Fasta
	GenBank_CP037924.fasta	Fasta
	allSpectra.HCD.FTMS.iso_0.apl	Other
	allSpectra.HCD.FTMS.iso_1.apl	Other

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1 - 5 of 9

Publications

Integrative structural analysis of the type III secretion system needle complex from Shigella flexneri.

Flacht Lara L Lunelli Michele M Kaszuba Karol K Chen Zhuo Angel ZA Reilly Francis J O' FJO Rappsilber Juri J Kosinski Jan J Kolbe Michael M

Protein science : a publication of the Protein Society 20230401 4

The type III secretion system (T3SS) is a large, transmembrane protein machinery used by various pathogenic gram-negative bacteria to transport virulence factors into the host cell during infection. Understanding the structure of T3SSs is crucial for future developments of therapeutics that could target this system. However, much of the knowledge about the structure of T3SS is available only for Salmonella, and it is unclear how this large assembly is conserved across species. Here, we combined ...[more]

PMID: 36790757

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