The immunopeptidome and proteome of DIPG

ABSTRACT: DIPG is a devastating paediatric and young adult brainstem tumour with no cure and a median overall survival of 9 months. Cellular immunotherapy approaches require specific targeting of unique and tumour specific cell surface antigens, however, there is a paucity of known targets for DIPG. Here we used a proteomics platform approach to interrogate an array of patient derived DIPG cell lines to facilitate a multi-omics based approach to identify cell surface protein candidates enriched or unique to DIPG.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Brain

SUBMITTER: Kirti Pandey  

LAB HEAD: Anthony Wayne Purcell

PROVIDER: PXD038271 | Pride | 2023-09-25

REPOSITORIES: Pride