Proteomics

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Immunopeptidomics of malignant mesothelioma to identify target antigens for T cell Immunotherapy


ABSTRACT: Immunoaffinity purification was performed on human mesothelioma cell lines NCI-H2452, NCI-H28, MSTO-211H and JL1, on murine mesothelioma cell line AB12, as well as on mesothelioma samples from two patients (including tumor and benign tissues). Thereafter Immunopeptidomics by Mass Spectrometry on a Tims TOF Pro revealed the MHC peptide landscape of mesothelioma.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)

TISSUE(S): Pleural Mesothelium, Mesothelium

DISEASE(S): Benign Mesothelioma,Malignant Mesothelioma

SUBMITTER: Rui Branca  

LAB HEAD: Janne Lehtiö

PROVIDER: PXD038273 | Pride | 2023-09-08

REPOSITORIES: Pride