Redifferentiated cardiomyocytes retain residual dedifferentiation signatures and are protected against ischaemic injury

ABSTRACT: Near-complete reversal of ERBB2-driven cardiomyocyte dedifferentiation is driven by the Hippo pathway, restoring contractility whilst long-lasting conferring cardioprotection.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Heart

SUBMITTER: Alon Savidor  

LAB HEAD: Eldad Tzahor

PROVIDER: PXD038450 | Pride | 2023-02-01

REPOSITORIES: Pride