Lung Cancer Exosomes Hypoxic v Normoxic
Ontology highlight
ABSTRACT:
INSTRUMENT(S): nanoACQUITY UPLC, LTQ Orbitrap XL ETD
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Lung
SUBMITTER: 
Richard Lobb
LAB HEAD: Andreas Moller
PROVIDER: PXD038587 | Pride | 2023-03-10
REPOSITORIES: Pride
Publications
An epithelial-to-mesenchymal transition induced extracellular vesicle prognostic signature in non-small cell lung cancer.
Lobb Richard J RJ Visan Kekoolani S KS Wu Li-Ying LY Norris Emma L EL Hastie Marcus L ML Everitt Sarah S Yang Ian A IA Bowman Rayleen V RV Siva Shankar S Larsen Jill E JE Gorman Jeffrey J JJ MacManus Michael M Leimgruber Antoine A Fong Kwun M KM Möller Andreas A
Communications biology 20230118 1
Despite significant therapeutic advances, lung cancer remains the leading cause of cancer-related death worldwide<sup>1</sup>. Non-small cell lung cancer (NSCLC) patients have a very poor overall five-year survival rate of only 10-20%. Currently, TNM staging is the gold standard for predicting overall survival and selecting optimal initial treatment options for NSCLC patients, including those with curable stages of disease. However, many patients with locoregionally-confined NSCLC relapse and di ...[more]
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