The interacted proteins of ALKBH5 and FTO identified by IP-mass
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ABSTRACT: Since m6A demethylases (FTO and ALKBH5) have been reported to be involved in pre-mRNA splicing regulation, we hypothesized that dynamic m6A distribution during mRNA maturation might involve removal of m6A in internal exons by FTO or ALKBH5 accompanied by splicing factors. To explore this we performed pull-down assays coupled with protein mass spectrometry.
INSTRUMENT(S): LTQ Orbitrap Elite
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: xin yang
LAB HEAD: Richard I. Gregory
PROVIDER: PXD038705 | Pride | 2022-12-09
REPOSITORIES: Pride
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