ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance

ABSTRACT: Affinity-purification coupled to mass spectrometry of GFP-ZNF432 expressed in wild-type and PARP1 KO 293T cells (with and without H2O2-induced DNA damage and PARP1 activation).

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Kidney

SUBMITTER: Jean-Philippe Gagne  

LAB HEAD: Guy G Poirier

PROVIDER: PXD038731 | Pride | 2024-01-26

REPOSITORIES: Pride