Immunization with lytic polysaccharide monooxygenase CbpD induces protective immunity against Pseudomonas aeruginosa pneumonia
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ABSTRACT: Bacterial lytic polysaccharide monooxygenases (LPMOs) are understudied in the context of infection disease. We demonstrated that Pseudomonas aeruginosa LPMO CbpD is a virulence determinant in pneumonia. Moreover, Mice immunized with CbpD generate robust antibody responses that provide protection against lethal lung infection
INSTRUMENT(S):
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Lung
SUBMITTER:
Jack-Ansgar Bruun
LAB HEAD: Victor Nizet
PROVIDER: PXD039298 | Pride | 2023-07-26
REPOSITORIES: Pride
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