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Ultra-fast and controlled capturing, loading, and release of extracellular vesicles by a portable microstructured electrochemical fluidic device

ABSTRACT: In this project two sets of DIA-based proteomics studies were performed to characterize the proteome of isolated extracellular vesicles. For each set, seven biological replicates were analyzed

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Joern Dengjel

LAB HEAD: Joern Dengjel

PROVIDER: PXD039342 | Pride | 2023-08-07

REPOSITORIES: Pride

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Ultrafast and Controlled Capturing, Loading, and Release of Extracellular Vesicles by a Portable Microstructured Electrochemical Fluidic Device.

Krivitsky Vadim V Krivitsky Adva A Mantella Valeria V Ben-Yehuda Greenwald Maya M Sankar Devanarayanan Siva DS Betschmann Jil J Bader Johannes J Zoratto Nicole N Schreier Kento K Feiss Sarah S Walker Dario D Dengjel Jörn J Werner Sabine S Leroux Jean-Christophe JC

Advanced materials (Deerfield Beach, Fla.) 20230919 44

Extracellular vesicles (EVs) are secreted by all living cells and are found in body fluids. They exert numerous physiological and pathological functions and serve as cargo shuttles. Due to their safety and inherent bioactivity, they have emerged as versatile therapeutic agents, biomarkers, and potential drug carriers. Despite the growing interest in EVs, current progress in this field is, in part, limited by relatively inefficient isolation techniques. Conventional methods are indeed slow, labor ...[more]

PMID: 37452635

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