Non-labelled proteomics expression analysis of PC-3 cells treated with transferrin conjugated gold nanoparticles

ABSTRACT: Nanoparticles-based therapeutics are being clinically translated for treating cancer. Meanwhile nanoparticles are increasingly being identified as impacting cell regulation and protein expression. Here, we sought to understand how a model of a relatively inert nanoparticle without any therapeutic agent itself interact with the cells and what are the key biological mechanisms.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Permanent Cell Line Cell, Cell Culture

DISEASE(S): Prostate Adenocarcinoma

SUBMITTER: Sonia Theresa Sebastian  

LAB HEAD: Associate Professor Ivan Kempson

PROVIDER: PXD039433 | Pride | 2023-10-24

REPOSITORIES: Pride