Proteomic profile of healthy human monocytes differentiated to macrophages with non-tumor or tumor cell-derived extracellular vesicles

ABSTRACT: To investigate the impact of tumor cell-derived extracellular vesicles on monocyte-macrophage differentiation, healthy monocytes were treated with EVs derived from two different pancreatic cancer cell lines and a non-tumoral pancreatic ductal epithelial cell line. Following differentiation to macrophages, proteomic analyses by mass spectrometry were performed on cells.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Monocyte, Pancreatic Ductal Carcinoma Cell, Blood

DISEASE(S): Pancreatic Ductal Adenocarcinoma

SUBMITTER: AUDEBERT Stephane  

LAB HEAD: Richard Tomasini, PhD

PROVIDER: PXD039439 | Pride | 2026-06-11

REPOSITORIES: Pride