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Mouse tumor cells secrete heterogenous particles including EVs, ENPs and VLPs into the extracellular medium - a proteome study

ABSTRACT: In addition to soluble proteins, cells secrete various types of membrane-enclosed extracellular vesicles (EVs: exosomes, ectosomes and others) and non-vesicular nanoparticles (ENPs) that are thought to play a role in intercellular communication. We exhaustively characterized the protein composition of secreted EVs and ENPs of murine tumor cell lines, including thorough separation of small EVs from co-isolated virus-like particles.

INSTRUMENT(S): Orbitrap Eclipse, Orbitrap Fusion

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Dendritic Cell, Breast

SUBMITTER: Vanessa Masson

LAB HEAD: Damarys Loew

PROVIDER: PXD039715 | Pride | 2023-11-27

REPOSITORIES: Pride

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