Discovery and characterization of a chemical probe targeting the zinc-finger ubiquitin-binding domain of HDAC6
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ABSTRACT: Cellular selectivity of a chemical probe for the UBD of HDAC6. A biotinylated analog of HDAC6 chemical probe SGC-UBD253 bound to streptavidin beads was used to enrich HDAC6 from cytoplasmic fraction of HEK293 lysate. A triplicate of each condition - competition with probe, control, DMSO - was done.
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Early Embryonic Cell
SUBMITTER:
Suzanne Ackloo
LAB HEAD: Cheryl H Arrowsmith
PROVIDER: PXD039880 | Pride | 2023-10-24
REPOSITORIES: Pride
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