Differential activation of NRF2 signaling pathway in renal cell carcinoma cells
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion Lumos
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Kidney
DISEASE(S): Kidney Cancer
SUBMITTER: 
Julius Nyalwidhe
LAB HEAD: Julius O Nyalwidhe
PROVIDER: PXD040083 | Pride | 2023-07-20
REPOSITORIES: Pride
Publications
Differential Activation of NRF2 Signaling Pathway in Renal-Cell Carcinoma Caki Cell Lines.
Hitefield Naomi L NL Mackay Stephen S Hays Lauren E LE Chen Shimin S Oduor Ian O IO Troyer Dean A DA Nyalwidhe Julius O JO
Biomedicines 20230324 4
Renal-cell carcinoma (RCC) is a heterogeneous disease consisting of several subtypes based on specific genomic profiles and histological and clinical characteristics. The subtype with the highest prevalence is clear-cell RCC (ccRCC), next is papillary RCC (pRCC), and then chromophobe RCC (chRCC). The ccRCC cell lines are further subdivided into prognostic expression-based subtypes ccA or ccB. This heterogeneity necessitates the development, availability, and utilization of cell line models with ...[more]
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