Characterization of RBM10 interactome in unchallenged and MK1775-treated cells

ABSTRACT: Mapping of RBM10-interactome using GFP-trap purification of EGFP-RBM10 expressed in HEK293T cells before and after WEE1 inhibition by MK1775. HEK293T expressing EGFP only or EGFP-RBM10 fusion (2 main isoforms) were left untreated or treated with 300nM MK1775 for 4 hours prior to GFP-trap enrichment and mass spectrometry analysis.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Lung, Epithelial Cell

DISEASE(S): Lung Adenocarcinoma

SUBMITTER: Feras Machour  

LAB HEAD: Nabieh Ayoub

PROVIDER: PXD040109 | Pride | 2024-07-16

REPOSITORIES: Pride