Norbergenin prevents LPS-induced inflammatory responses in macrophages through inhibiting NFκB, MAPK and STAT3 activation, and blocking metabolic reprogramming
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ABSTRACT: Inflammation is thought to be a key cause of many chronic diseases. However, current therapeutic agents to control inflammation have limited long-term use potential due to various side effects. This study aimed to determine the preventive effects of norbergenin on LPS-induced inflammation and elucidate the underlying mechanisms.
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Cell Culture, Macrophage
SUBMITTER: Zhengnan Cai
LAB HEAD: Wolfram Weckwerth
PROVIDER: PXD040202 | Pride | 2023-04-10
REPOSITORIES: Pride
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