Distribution of phosphorylated alpha-synuclein in non-diseased brain implicates olfactory bulb mitral cells in synucleinopathy pathogenesis.

ABSTRACT: Project aim was to identify protein-protein interactions of the post-translationally modified form of alpha-synuclein. In situ proximity labeling (BAR) was used to enrich for protein-protein interactions. We performed BAR on wild-type and alpha-synuclein knockout olfactory bulb tissues. We include negative capture conditions, where the primary antibody was omitted.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Brain

DISEASE(S): Disease Free

SUBMITTER: Bryan Killinger  

LAB HEAD: Bryan Andrew Killinger

PROVIDER: PXD040392 | Pride | 2023-03-27

REPOSITORIES: Pride