Development of multifunctional synthetic nucleosomes

ABSTRACT: Various proteins bind to chromatin to regulate DNA and its associated processes such as replication, transcription, and damage repair. The identification and characterization of these chromatin-associating proteins remain a challenge, as their interactions with chromatin often occur within the context of the local nucleosome or chromatin structure, which makes conventional peptide-based strategies unsuitable.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: ZHENG LIU  

LAB HEAD: Xiang David Li

PROVIDER: PXD040459 | Pride | 2023-05-04

REPOSITORIES: Pride