Integrated with Proteome-sequencing, bulk RNA-sequencing and Single cell RNA-sequencing to identify potential biomarkers in different grades of intervertebral disc degeneration
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ABSTRACT: We selected humann intervertebral disc samples to perform proteomics analysis. There were 1 case of grade I , 1 case of grade II, 3 cases of grade Ⅲ and 3 cases of grade Ⅳ according to Pfirrmann classfication. RNA seqencing analysis and single-cell RNA sequencing were integrated with proteomics data to identify the hub genes for intervertebral disc degeneration using bioinformatic method.
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
SUBMITTER:
Xiao Yang
LAB HEAD: Lei Chu
PROVIDER: PXD040593 | Pride | 2023-05-10
REPOSITORIES: Pride
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