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Effect of Edurans secretome of human microbiome

ABSTRACT: A rapid ex vivo microbiome assay and metaproteomics approach was used for evaluating the impacts of E. durans derived secretome on a human gut microbiome cultured in vitro.

INSTRUMENT(S): Q Exactive

ORGANISM(S): Metagenome

SUBMITTER: Xu Zhang

LAB HEAD: Daniel Figeys

PROVIDER: PXD040751 | Pride | 2024-01-31

REPOSITORIES: Pride

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The Influence of Protein Secretomes of Enterococcus durans on ex vivo Human Gut Microbiome.

Comerlato Carolina Baldisserotto CB Zhang Xu X Walker Krystal K Mayne Janice J Figeys Daniel D Brandelli Adriano A

Probiotics and antimicrobial proteins 20230817

The gut microbiome plays a critical role to all animals and humans health. Methods based on ex vivo cultures are time and cost-effective solutions for rapid evaluation of probiotic effects on microbiomes. In this study, we assessed whether the protein secretome from the potential probiotic Enterococcus durans LAB18S grown on fructoligosaccharides (FOS) and galactoligosaccharides (GOS) had specific effects on ex vivo cultured intestinal microbiome obtained from a healthy individual. Metaproteomic ...[more]

PMID: 37589783

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