The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions

ABSTRACT: Molecular chaperones govern proteome health to support cell homeostasis. An essential eukaryotic component of the chaperone system is Hsp90. Using a chemical-biology approach we characterized the features driving the Hsp90 physical interactome.

INSTRUMENT(S):

ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)

SUBMITTER: Janhavi Kolhe  

LAB HEAD: Brian Freeman

PROVIDER: PXD040875 | Pride | 2023-08-10

REPOSITORIES: Pride