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A DOMON domain-cytochrome b561 protein acts as a ferric reductase in iron homeostasis and impacts primary root growth under phosphate deficiency

ABSTRACT: An Arabidopsis mutant in the ER chaperones Calnexins has shown reduced primary root growth under phosphate deficiency. In order to determine which protein(s) could be implicated in this phenotype, we have performed a proteomic experiment to identify proteins differentially abundant in roots of the calnexin mutants versus wild-type.

INSTRUMENT(S): Orbitrap Fusion

ORGANISM(S): Arabidopsis Thaliana (mouse-ear Cress)

TISSUE(S): Root

SUBMITTER: Manfredo Quadroni

LAB HEAD: Yves Poirier

PROVIDER: PXD040981 | Pride | 2023-11-13

REPOSITORIES: Pride

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A CYBDOM protein impacts iron homeostasis and primary root growth under phosphate deficiency in Arabidopsis.

Clúa Joaquín J Montpetit Jonatan J Jimenez-Sandoval Pedro P Naumann Christin C Santiago Julia J Poirier Yves Y

Nature communications 20240111 1

Arabidopsis primary root growth response to phosphate (Pi) deficiency is mainly controlled by changes in apoplastic iron (Fe). Upon Pi deficiency, apoplastic Fe deposition in the root apical meristem activates pathways leading to the arrest of meristem maintenance and inhibition of cell elongation. Here, we report that a member of the uncharacterized cytochrome b561 and DOMON domain (CYBDOM) protein family, named CRR, promotes iron reduction in an ascorbate-dependent manner and controls apoplast ...[more]

PMID: 38212368

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