Proteins that interact with CLK2 (WT) or CLK2 (T343A)
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ABSTRACT: Our results show that CLK2 undergoes liquid-liquid phase separation (LLPS) in response to heat shock stress. Phosphorylation of CLK2 at T343 prevents the LLPS of CLK2. To identify the proteins that recruited to the CLK2 condensates, we immunoprecipitated CLK2 (WT) or (T343A) proteins with FLAG antibody and performed mass spectrometry to detect the interacting proteins.
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Permanent Cell Line Cell, Cell Culture
DISEASE(S): Glioblastoma
SUBMITTER: Wei Wang
LAB HEAD: Wei Wang
PROVIDER: PXD040997 | Pride | 2023-11-06
REPOSITORIES: Pride
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