Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Homo Sapiens (human)
SUBMITTER: Sehyun Chae
LAB HEAD: Sehyun Chae
PROVIDER: PXD041077 | Pride | 2023-06-30
REPOSITORIES: Pride
Lee Saseong S Choi Eunbyeol E Chae Sehyun S Koh Jung Hee JH Choi Yoolim Y Kim Jung Gon JG Yoo Seung-Ah SA Hwang Daehee D Kim Wan-Uk WU
Annals of the rheumatic diseases 20230515 8
<h4>Objectives</h4>'Invasive pannus' is a pathological hallmark of rheumatoid arthritis (RA). This study aimed to investigate secretome profile of synovial fibroblasts of patients with RA (RA-FLSs), a major cell type comprising the invasive pannus.<h4>Methods</h4>Secreted proteins from RA-FLSs were first identified using liquid chromatography-tandem mass spectrometry analysis. Ultrasonography was performed for affected joints to define synovitis severity at the time of arthrocentesis. Expression ...[more]