Identification of proteins bound with RPA194 at rDNA loci post radiation in breast cancer cells

ABSTRACT: Following radiation damage, cells resume ribosome biogenesis for survival. We combined chromatin immunoprecipitation (ChIP) with mass spectrometry to identify key binding partners of RPA194 (the major subunit of RNA polI) at the rDNA loci in response to irradiation.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Cell Culture

DISEASE(S): Breast Cancer

SUBMITTER: Brandon Metge  

LAB HEAD: Lalita Samant

PROVIDER: PXD041472 | Pride | 2023-07-20

REPOSITORIES: Pride