Integrated multi-omics approach reveals the role of SPEG in skeletal muscle biology including its relationship with myospryn complex

ABSTRACT: We applied multi-omics approaches (interactomic, proteomic, phosphoproteomic, and transcriptomic analyses) to assess underlying molecular pathways impacted by SPEG using mouse skeletal muscle from 2-month-old WT (n=4) and Speg-CKO (n=3) mice.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): Skeletal Muscle

DISEASE(S): Centronuclear Myopathy 5

SUBMITTER: Qifei Li  

LAB HEAD: Pankaj B Agrawal

PROVIDER: PXD041692 | Pride | 2024-06-22

REPOSITORIES: Pride