Cell surface-specific N-glycoproteomics
Ontology highlight
ABSTRACT: To understand the cellular functions of glycans and to exploit them as clinical targets it is essential to acquire information on their cell surface exposure. Here, we developed a sensitive and specific mass spectrometry method to globally study the N-glycoforms displayed at individual protein sites on the cell surface. This offers a valuable tool to discriminate between functionally relevant glycans and biosynthetic intermediates for future cellular glycoproteomic analyses.
INSTRUMENT(S):
ORGANISM(S): Homo Sapiens (human)
TISSUE(S): Keratinocyte, Skin
SUBMITTER:
Noortje de Haan
LAB HEAD: Hans Wandall
PROVIDER: PXD042172 | Pride | 2024-01-26
REPOSITORIES: Pride
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