Proteomics

Dataset Information

Cell surface-specific N-glycoproteomics


ABSTRACT: To understand the cellular functions of glycans and to exploit them as clinical targets it is essential to acquire information on their cell surface exposure. Here, we developed a sensitive and specific mass spectrometry method to globally study the N-glycoforms displayed at individual protein sites on the cell surface. This offers a valuable tool to discriminate between functionally relevant glycans and biosynthetic intermediates for future cellular glycoproteomic analyses.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Keratinocyte, Skin

SUBMITTER: Noortje de Haan  

LAB HEAD: Hans Wandall

PROVIDER: PXD042172 | Pride | 2024-01-26

REPOSITORIES: Pride

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