Ontology highlight
ABSTRACT:
INSTRUMENT(S): LTQ Orbitrap
ORGANISM(S): Saccharomyces Cerevisiae (baker's Yeast)
TISSUE(S): Cell Culture
SUBMITTER: Eric Bonneil
LAB HEAD: Brenda Andrews
PROVIDER: PXD042259 | Pride | 2023-08-10
REPOSITORIES: Pride
Suresh Harsha Garadi HG Bonneil Eric E Albert Benjamin B Dominique Carine C Costanzo Michael M Pons Carles C David Masinas Myra Paz MP Shuteriqi Ermira E Shore David D Henras Anthony K AK Thibault Pierre P Boone Charles C Andrews Brenda J BJ
bioRxiv : the preprint server for biology 20230504
Ribosome assembly requires precise coordination between the production and assembly of ribosomal components. Mutations in ribosomal proteins that inhibit the assembly process or ribosome function are often associated with Ribosomopathies, some of which are linked to defects in proteostasis. In this study, we examine the interplay between several yeast proteostasis enzymes, including deubiquitylases (DUBs), Ubp2 and Ubp14, and E3 ligases, Ufd4 and Hul5, and we explore their roles in the regulatio ...[more]