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Proteomic changes of CD19+ B Lymphocytes in COVID-19 Patients

ABSTRACT: The immune response to SARS-CoV-2 varies among patients. We used proteomic analysis to study CD19+ lymphocytes, which are important for the immune response. By comparing the proteomes of CD19+ cells from healthy individuals and COVID-19 patients, we discovered proteins and signaling pathways involved in the immune response during COVID-19. This knowledge improves our understanding of immune dysregulation in COVID-19 and can help develop targeted therapies. Our research also explores the role of CD19+ lymphocytes in COVID-19 and identifies potential biomarkers. Overall, our findings contribute to understanding COVID-19 immunology and inform future research efforts.

INSTRUMENT(S): Orbitrap Exploris 480

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): B-lymphocyte Antigen Cd19 (human), Blood

DISEASE(S): Covid-19

SUBMITTER: Miroslav Marcin

LAB HEAD: Ján Sabo

PROVIDER: PXD042938 | Pride | 2023-09-24

REPOSITORIES: Pride

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