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TMT Multiplexing-Based Quantitative Analysis of Pathogenic Th2 Proteomes.

ABSTRACT: To investigate the regulation of pathogenic Th2 (pTh2) cells and the role of histone deacetylase 1 (HDAC1) in the respective processes, we used a new in vitro protocol for generating pTh2 cells and performed qunatitative mass spectrometry analysis based on TMTpro 16plex multiplexing to analyze proteomes. We profiled classical Th2 and pTh2 cells from wild type (WT) mice and mice with a T cell-specific deletion of HDAC1 (HDAC1-cKO).

INSTRUMENT(S): Orbitrap Eclipse

ORGANISM(S): Mus Musculus (mouse)

TISSUE(S): T Cell, Blood

SUBMITTER: Wolfgang Reiter

LAB HEAD: Dr. Markus Hartl

PROVIDER: PXD042975 | Pride | 2025-02-20

REPOSITORIES: Pride

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			Action	DRS
	20220408_Eclipse_LC6_Khan_Boucheron_MPLGmbH_Academic_TMT16_proteome_01_cv40.raw	Raw
	20220408_Eclipse_LC6_Khan_Boucheron_MPLGmbH_Academic_TMT16_proteome_01_cv55.raw	Raw
	20220408_Eclipse_LC6_Khan_Boucheron_MPLGmbH_Academic_TMT16_proteome_01_cv70.raw	Raw
	20220408_Eclipse_LC6_Khan_Boucheron_MPLGmbH_Academic_TMT16_proteome_02_cv40.raw	Raw
	20220408_Eclipse_LC6_Khan_Boucheron_MPLGmbH_Academic_TMT16_proteome_02_cv55.raw	Raw

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