Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation

ABSTRACT: GM1-ganglioside, an abundant GSL in neuronal membranes, is integral to ER-PM junctions where it interacts with synaptic proteins/receptors and regulates Ca2+ signaling.

INSTRUMENT(S):

ORGANISM(S): Mus Musculus (mouse)

SUBMITTER: Ashutosh Mishra  

LAB HEAD: Alessandra D'Azzo-Grosveld

PROVIDER: PXD042994 | Pride | 2024-03-19

REPOSITORIES: Pride