Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation
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ABSTRACT: GM1-ganglioside, an abundant GSL in neuronal membranes, is integral to ER-PM junctions where it interacts with synaptic proteins/receptors and regulates Ca2+ signaling.
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Mus Musculus (mouse)
SUBMITTER: Ashutosh Mishra
LAB HEAD: Alessandra D'Azzo-Grosveld
PROVIDER: PXD042994 | Pride | 2024-03-19
REPOSITORIES: Pride
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