Isolated Mitochondria from Cold and TN Mice LC MS/MS
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Fusion
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Cell Culture
SUBMITTER: 
Qin Fu
LAB HEAD: Qin Fu
PROVIDER: PXD043251 | Pride | 2023-10-24
REPOSITORIES: Pride
Publications
Nipsnap1-A regulatory factor required for long-term maintenance of non-shivering thermogenesis.
Liu Yang Y Qu Yue Y Cheng Chloe C Tsai Pei-Yin PY Edwards Kaydine K Xue Siwen S Pandit Supriya S Eguchi Sakura S Sanghera Navneet N Barrow Joeva J JJ
Molecular metabolism 20230707
<h4>Objective</h4>The activation of non-shivering thermogenesis (NST) has strong potential to combat obesity and metabolic disease. The activation of NST however is extremely temporal and the mechanisms surrounding how the benefits of NST are sustained once fully activated, remain unexplored. The objective of this study is to investigate the role of 4-Nitrophenylphosphatase Domain and Non-Neuronal SNAP25-Like 1 (Nipsnap1) in NST maintenance, which is a critical regulator identified in this study ...[more]
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