SWATH proteomics of NMN effects

ABSTRACT: Nicotinamide mononucleotide (NMN) has emerged as a promising therapeutic intervention for age-related disorders, including Type 2 Diabetes. In this study, we investigated the effects of NMN treatment on glucose uptake and its underlying mechanisms in mouse tissues (muscle, liver, brain and adipose tissue) and cell lines (HepG2 and C2C12). Through a comprehensive proteomic analysis, we uncovered a series of distinct organ-specific effects that contribute to the observed improvements in glucose metabolism.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human) Mus Musculus (mouse)

TISSUE(S): Brain, Liver, Muscle, Adipose Tissue

DISEASE(S): Type 2 Diabetes Mellitus

SUBMITTER: Roua Popescu  

LAB HEAD: George Catalin Marinescu

PROVIDER: PXD043257 | Pride | 2024-06-16

REPOSITORIES: Pride