Dataset Information

Proteomics Profiles of the placenta Reveal the fetal calf growth-Related Candidate Biomarkers of Shandong black cattle

ABSTRACT: The placenta is a dynamic reproductive organ for cattle reproduction and is indispensable for embryonic blood supply, nutrition transportation, and fetal calf development, and it directly affects the development of fetal calf in utero. However, the detailed molecular mechanism of placenta act on fetal calf still remains unclear.In the present study,we used the proteome of placenta to identify the key gene and protein in Low weight(LW) fetal calves and High weight(HW) fetal calves, and reveal the fetal calf growth-related candidate biomarkers by integrative analysis.Placenta proteomics provide new insight into the physiological mechanisms and potential biomarkers for fetal calf development in utero,which can be employed to enhance breeding efficiency and genetic improvement in cattle.

INSTRUMENT(S):

ORGANISM(S): Bos Taurus (bovine)

TISSUE(S): Placenta

SUBMITTER: zhenpeng chen

LAB HEAD: Yajuan Dong

PROVIDER: PXD043483 | Pride | 2025-05-06

REPOSITORIES: Pride

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			Action	DRS
	1.raw.zip	Raw
	A-Za-z0-9.xls	Xls
	A-Za-z0-99.xls	Xls

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Publications

Combining Transcriptomics and Proteomics to Screen Candidate Genes Related to Bovine Birth Weight.

Wang Xiuyuan X Liu Ruili R Chen Zhenpeng Z Zhang Renzheng R Mei Yanfang Y Miao Xiuping X Bai Xuejin X Dong Yajuan Y

Animals : an open access journal from MDPI 20240923 18

The placenta is a vital organ in bovine reproduction, crucial for blood supply, nutrient transport, and embryonic development. It plays an essential role in the intrauterine growth of calves. However, the molecular mechanisms governing placental function in calves remain inadequately understood.<h4>Methods</h4>We established transcriptome and proteome databases for low-birth-weight (LB) and high-birth-weight (HB) calf placentae, identifying key genes and proteins associated with birth weight thr ...[more]

PMID: 39335340

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