Proteomics

Dataset Information

0

Identifying the mechanism of platelet activation by platelet factor 4 (PF4) a.k.a CXCL4


ABSTRACT: We discovered that platelets become activated by platelet factor 4 and have looked into how this is the case. We used phosphoproteomics to identify proteins that were phosphorylated in a band on a Western blot at 95 kDa and identified phospho STAT5. We have subsequently shown that PF4 activates platelets through the JAK/STAT pathway.

INSTRUMENT(S): Q Exactive HF

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Platelet

SUBMITTER: Richard Buka  

LAB HEAD: Phillip L R Nicolson

PROVIDER: PXD043558 | Pride | 2024-06-16

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
2022-07-29_RBuka_1Resting.mgf Mgf
2022-07-29_RBuka_1Resting.msf Msf
2022-07-29_RBuka_1Resting.mzML Mzml
2022-07-29_RBuka_1Resting.mzid.gz Mzid
2022-07-29_RBuka_1Resting.raw Raw
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