Mouse embryonic tail tendon bundle time series
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Orbitrap Exploris 480
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Tendon
SUBMITTER: 
Joan Chang
LAB HEAD: Joan Chang
PROVIDER: PXD043811 | Pride | 2023-07-19
REPOSITORIES: Pride
Publications
Modeling collagen fibril self-assembly from extracellular medium in embryonic tendon.
Revell Christopher K CK Herrera Jeremy A JA Lawless Craig C Lu Yinhui Y Kadler Karl E KE Chang Joan J Jensen Oliver E OE
Biophysical journal 20230705 16
Collagen is a key structural component of multicellular organisms and is arranged in a highly organized manner. In structural tissues such as tendons, collagen forms bundles of parallel fibers between cells, which appear within a 24-h window between embryonic day 13.5 (E13.5) and E14.5 during mouse embryonic development. Current models assume that the organized structure of collagen requires direct cellular control, whereby cells actively lay down collagen fibrils from cell surfaces. However, su ...[more]
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