In-depth proteome analysis of renal fibrosis in primary cultured human-derived kidney cells

ABSTRACT: Biomarker assessments based on kidney tissue evaluations show a direct correlation with renal fibrosis, but are limited by their invasive nature. Consequently, there is a growing interest in noninvasive biomarkers based on urine and blood samples. However, the utility of urine samples is limited by variations in concentrations and challenges in determining the specific origin of the detected substances, while blood samples may reflect changes in multiple organs, complicating biomarker evaluations. To address these issues, we performed a proteomics study to identify potential biomarkers of renal fibrosis using primary cultured human-derived kidney cells.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Kidney

DISEASE(S): Chronic Kidney Disease

SUBMITTER: Dohyun Han  

LAB HEAD: Dohyun Han

PROVIDER: PXD043922 | Pride | 2025-05-06

REPOSITORIES: Pride