Global Proteomic Profiling of Pediatric AML: A Pilot Study

ABSTRACT: Acute Myeloid Leukemia (AML) is a heterogeneous disease with several recurrent cytogenetic abnormalities. Despite genomics and transcriptomics profiling efforts to understand AML’s heterogeneity, studies focused on the proteomic profiles associated with pediatric AML cytogenetic features remain limited. Furthermore, the majority of biological functions within cells are operated by proteins (i.e., enzymes) and most drugs target the proteome rather than the genome or transcriptome, thus, highlighting the significance of studying proteomics.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Leukocyte, Bone Marrow, Blood

DISEASE(S): Acute Leukemia

SUBMITTER: Haiyan Tan  

LAB HEAD: Junmin Peng

PROVIDER: PXD043982 | Pride | 2023-09-26

REPOSITORIES: Pride