Plasma Proteomic Characterization of Colorectal Cancer Patients with FOLFOX Chemotherapy

ABSTRACT: Colorectal Cancer (CRC) is one of most common cancers in the world and a main treatment in postoperative chemotherapy is oxaliplatin and fluorouracil (FOLFOX), But the effect is different among CRC patients. In this study, LC-MS/MS strategy was used to profile the plasma proteome in FOLFOX benefit and futile group. As a result, a panel of plasma proteins by machine learning from our data was verified for a possible prediction tool in postdiagnosis.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Plasma

DISEASE(S): Colon Cancer

SUBMITTER: Keren Zhang  

LAB HEAD: Ruijun Tian

PROVIDER: PXD044201 | Pride | 2024-05-21

REPOSITORIES: Pride