Proteomics

Dataset Information

Eye proteome of Drosophila melanogaster

ABSTRACT: We report the proteome composition of the Drosophila eye – a compound organ that is highly enriched in membrane proteins. The fly eye is a popular model to study the physiology of vision by means of genetic, pharmacological, and dietary interference.While the eye transcriptome and development-related changes of gene expression profiles have been extensively studied, little is known about the eye proteome.we employed GeLC-MS/MS to identify and rank the abundances of 3516 eye proteins. Moreover, we applied our MS Western method to determine the absolute (molar) abundances of a related set of proteins that are important for photoreceptor structure (including maintenance) and function (phototransduction). Altogether, we provide a comprehensive and expandable proteomics resource that will be valuable for a variety of studies of ocular biochemistry, physiology, and development.

INSTRUMENT(S):

ORGANISM(S): Drosophila Melanogaster (fruit Fly)

TISSUE(S): Compound Eye

SUBMITTER: Mukesh Kumar  

LAB HEAD: Andrej Shevchenko

PROVIDER: PXD044845 | Pride | 2024-08-09

REPOSITORIES: Pride

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20160618_DmDiet_3rdRound_BR1_NF_GS_01_D3012_BSA_1pm_23ul_Dionex_120min_01.raw Raw
20160618_DmDiet_3rdRound_BR1_NF_GS_01_D3012_BSA_1pm_23ul_Dionex_120min_02.raw Raw
20160618_DmDiet_3rdRound_BR1_NF_GS_02_D3012_BSA_1pm_23ul_Dionex_120min_01.raw Raw
20160618_DmDiet_3rdRound_BR1_NF_GS_02_D3012_BSA_1pm_23ul_Dionex_120min_02.raw Raw
20160618_DmDiet_3rdRound_BR1_NF_GS_03_D3012_BSA_1pm_23ul_Dionex_120min_01.raw Raw
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