Ontology highlight
ABSTRACT:
INSTRUMENT(S): Q Exactive
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Blood Serum, Intestinal Juice, Colon
SUBMITTER: Dan Xu
LAB HEAD: Raffaele Mezzenga
PROVIDER: PXD045698 | Pride | 2023-10-30
REPOSITORIES: Pride
Xu Dan D Zhou Jiangtao J Soon Wei Long WL Kutzli Ines I Molière Adrian A Diedrich Sabine S Radiom Milad M Handschin Stephan S Li Bing B Li Lin L Sturla Shana J SJ Ewald Collin Y CY Mezzenga Raffaele R
Nature communications 20231026 1
Food protein amyloid fibrils have superior technological, nutritional, sensorial, and physical properties compared to native monomers, but there is as yet insufficient understanding of their digestive fate and safety for wide consumption. By combining SDS-PAGE, ELISA, fluorescence, AFM, MALDI-MS, CD, microfluidics, and SAXS techniques for the characterization of β-lactoglobulin and lysozyme amyloid fibrils subjected to in-vitro gastrointestinal digestion, here we show that either no noticeable c ...[more]