LC-MS/MS analysis on in-vivo mice gastrointestinal digests
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ABSTRACT: Food protein amyloid fibrils have superior technological,nutritional,sensorial,and physical properties compared to native monomers, butthere is yet insufficient understanding of their digestive fate and safety for wide consumption.By combining SDS,ELISA,fluorenscence,AFM, MALDI-MS, CD microfluidics,and SAXS techniques for the characterization of blg and lysozyme amyloid fibrils subjected to in-vitro gastrointestinal digestion.LC-MS/MS analysis on the fate of blg/lysozyme amyloid fibrils digested in vivo by mice was applied to verify our in vitro results.
INSTRUMENT(S):
ORGANISM(S): Mus Musculus (mouse)
TISSUE(S): Blood Serum, Intestinal Juice, Colon
SUBMITTER:
Dan Xu
LAB HEAD: Raffaele Mezzenga
PROVIDER: PXD045698 | Pride | 2023-10-30
REPOSITORIES: Pride
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