Proteomics

Dataset Information

The ISG Atlas: A Loss-Of-Function Analysis Characterizes Antiviral Properties of Interferon Stimulated Genes


ABSTRACT: The innate immune system requires the activity of interferon-stimulated genes (ISGs) to mount its protective response against viruses and other pathogens. However, the sensitivity of ISGs against viruses varies widely, and the spectrum of antiviral activities of ISGs is only partially understood. Utilizing an arrayed, time-resolved loss-of-function screen, we systematically investigated 285 ISGs for their virus-modulating activity against eight viruses.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Cell Culture

SUBMITTER: Sabri Hamad  

LAB HEAD: Andreas Pichlmair

PROVIDER: PXD045783 | Pride | 2026-03-09

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
20201117_QEp5_KaKr_SA_FP_1.raw Raw
20201117_QEp5_KaKr_SA_FP_10.raw Raw
20201117_QEp5_KaKr_SA_FP_100.raw Raw
20201117_QEp5_KaKr_SA_FP_101.raw Raw
20201117_QEp5_KaKr_SA_FP_102.raw Raw
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