Stoichiometric and structural analyses support the 48:12 model of the human pyruvate dehydrogenase complex core

ABSTRACT: Chemical cross-linking coupled to mass spectrometry using the amine-reactive BS3 reagent was used to study the organization of the human pyruvate dehydrogenase complex core consisting of multiple copies of dihydrolipoamide acetyltransferase (E2) and dihydrolipoamide dehydrogenase-binding protein (E3BP) assembled into a 60-mer complex.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

SUBMITTER: Alexander Leitner  

LAB HEAD: Alexander Leitner

PROVIDER: PXD045858 | Pride | 2024-05-15

REPOSITORIES: Pride