Dynamic proximity based interactome of the transcription factor RELA to identify gene-regulatory networks revealed

ABSTRACT: Using p65-miniTurbo fusion proteins in HeLa cells, we identified by biotin tagging > 350 RELA interactors from untreated and IL-1a-stimulated cells, including many TFs (47 % of all interactors) and > 50 epigenetic regulators belonging to different classes of chromatin remodeling complexes.

INSTRUMENT(S):

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Epithelial Cell, Colon

DISEASE(S): Colon Cancer

SUBMITTER: Axel Weber  

LAB HEAD: Michael Kracht

PROVIDER: PXD045888 | Pride | 2024-11-04

REPOSITORIES: Pride